Dimethocaine

Dimethocaine (Larocaine) is a local anesthetic with stimulant properties that some studies have shown to be half the potency of cocaine.[1][2][3]
Dimethocaine
Dimethocaine
Dimethocaine-structure.svg
Clinical data
ATC code none
Legal status
Legal status
Identifiers
CAS Number 94-15-5 YesY
553-63-9 (HCl)
PubChem (CID) 7177
ChemSpider 6909 N
UNII R3L4A6GOWZ YesY
Chemical and physical data
Formula C16H26N2O2
Molar mass 278.39 g/mol
3D model (Jmol) Interactive image
Melting point 64 to 65 °C (147 to 149 °F)
 NYesY (what is this?)  (verify)

Dimethocaine (Larocaine) is a local anesthetic with stimulant properties that some studies have shown to be half the potency of cocaine.[1][2][3]

When a product sold online in the UK in June 2010, advertised as dimethocaine was tested, it was found to in fact be a mixture of caffeine and lidocaine,[4] and the lack of any dopaminergic stimulant ingredient in such mixes may explain the limited recreational effects reported by many users. Other samples tested have however been shown to contain genuine dimethocaine, and one branded "bath salt" product containing primarily dimethocaine as the active ingredient, was noted to have been particularly subject to abuse by intravenous drug users in Ireland.[5]

See also

References

  1. ^ Wilcox, KM; Kimmel, HL; Lindsey, KP; Votaw, JR; Goodman, MM; Howell, LL (2005). "In vivo comparison of the reinforcing and dopamine transporter effects of local anesthetics in rhesus monkeys and rabbits." (PDF). Synapse. 58 (4): 220–8. doi:10.1002/syn.20199. PMID 16206183. Archived from the original (PDF) on 2010-06-11. 
  2. ^ Woodward JJ, Compton DM, Balster RL, Martin BR (April 1995). "In vitro and in vivo effects of cocaine and selected local anesthetics on the dopamine transporter". Eur. J. Pharmacol. 277 (1): 7–13. doi:10.1016/0014-2999(95)00042-J. PMID 7635175. 
  3. ^ Rigon, AR; Takahashi, RN (1996). "Stimulant activities of dimethocaine in mice: reinforcing and anxiogenic effects.". Psychopharmacology. 127 (4): 323–7. doi:10.1007/s002130050093. PMID 8923567. 
  4. ^ Brandt, S. D.; Sumnall, H. R.; Measham, F.; Cole, J. (2010). "Second generation mephedrone. The confusing case of NRG-1". BMJ. 341: c3564. doi:10.1136/bmj.c3564. PMID 20605894. 
  5. ^ An overview of new psychoactive substances and the outlets supplying them Archived November 25, 2011, at the Wayback Machine.
منبع: ویکی پدیا

پربازدیدترین

جدیدترین ها

Image

WJVL

WJVL (99.9 FM) is a radio station licensed to Janesville, Wisc ... ویکی پدیا
Image

Apai

Apai is one of four small villages on Manono Island in Samoa. ... ویکی پدیا
Image

T&L

T&L(Transform & lighting),是指坐标转换和光源。 ویکی پدیا
Image

AIML

AIML, or Artificial Intelligence Markup Language, is an XML di ... ویکی پدیا
Image

Juma

Juma may refer to: ویکی پدیا

جدیدترین ها در این موضوع

Image

WJVL

WJVL (99.9 FM) is a radio station licensed to Janesville, Wisc ... ویکی پدیا
Image

Apai

Apai is one of four small villages on Manono Island in Samoa. ... ویکی پدیا
Image

T&L

T&L(Transform & lighting),是指坐标转换和光源。 ویکی پدیا
Image

AIML

AIML, or Artificial Intelligence Markup Language, is an XML di ... ویکی پدیا
Image

Juma

Juma may refer to: ویکی پدیا

سایر مطالب

بالا
Powered by TayaCMS